Acitrom®
Is a coumarin derivative and functions as vitamin K antagonist. Vitamin K antagonists produce their anticoagulant effect by inhibition of the vitamin K-epoxide-reductase.4-6
read moreHow Does Acitrom® Act?
- Is structurally similar to vitamin K4-6
- Competitively inhibits the enzyme vitamin K-epoxide reductase4-6
Acitrom®
Acenocoumarol Vs. Warfarin
Acitrom® (Acenocoumarol) is twice as potent as warfarin.
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Acitrom® Offers More Stable INR2
The mean percentage of INR-s in the therapeutic range of 2-3 was 49 ± 22.6% for warfarin and 56 ± 26.8% for acenocoumarol (p < 0.05).
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Acitrom® Provides Superior Anticoagulant Effect7,8
Acenocoumarol has a rapid onset of action, and the effect is maintained for 15–20 hours. Such properties offer great advantages to its clinical use.
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Acitrom® Has Shorter Half-Life4,9
Good maintenance of prothrombin time over 24 hours yet rapid reversal of anticoagulant action if needed.